| Assay ID | Title | Year | Journal | Article |
|---|
| AID326306 | Increase in glucocerebrosidase activity in human N370S mutant cells at 40 uM by pulse-chase assay | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-07, Volume: 104, Issue:32
| Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease. |
| AID702064 | Inhibition of glucocerebrosidase N370S mutant using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured after 20 mins by fluorimetric analysis | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Discovery, structure-activity relationship, and biological evaluation of noninhibitory small molecule chaperones of glucocerebrosidase. |
| AID326301 | Effect on recombinant wild-type glucocerebrosidase | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-07, Volume: 104, Issue:32
| Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease. |
| AID702061 | Inhibition of glucocerebrosidase N370S mutant in Gaucher patient spleen homogenate using resorufin beta-D-glucopyranoside as substrate incubated for 5 mins prior to substrate addition measured after 20 mins by fluorimetric analysis | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Discovery, structure-activity relationship, and biological evaluation of noninhibitory small molecule chaperones of glucocerebrosidase. |
| AID326300 | Inhibition of recombinant wild-type glucocerebrosidase | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-07, Volume: 104, Issue:32
| Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease. |
| AID326315 | Increase in glucocerebrosidase protein localization in lysosomes of human N370S cells at 40 uM | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-07, Volume: 104, Issue:32
| Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease. |
| AID326302 | Inhibition of rice alpha-glucosidase upto 77 uM | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-07, Volume: 104, Issue:32
| Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease. |
| AID326305 | Inhibition of green coffee beans alpha-galactosidase upto 77 uM | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-07, Volume: 104, Issue:32
| Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease. |
| AID326311 | Increase in glucocerebrosidase activity in human N370S mutant cells at <13.3 uM by pulse-chase assay | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-07, Volume: 104, Issue:32
| Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease. |
| AID326312 | Inhibition of glucocerebrosidase activity in human wild-type fibroblasts at <13.3 uM by pulse-chase assay | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-07, Volume: 104, Issue:32
| Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease. |
| AID326303 | Inhibition of human beta-N-acetylglucosaminidase upto 77 uM | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-07, Volume: 104, Issue:32
| Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease. |
| AID326308 | Increase in glucocerebrosidase activity in human wild-type fibroblasts at 40 uM by pulse-chase assay | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-07, Volume: 104, Issue:32
| Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease. |
| AID702063 | Inhibition of wild type glucocerebrosidase in human spleen homogenate using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured after 20 mins by fluorimetric analysis | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Discovery, structure-activity relationship, and biological evaluation of noninhibitory small molecule chaperones of glucocerebrosidase. |
| AID702066 | Inhibition of wild type glucocerebrosidase using 4-methylumbellifereno-Glc as substrate incubated for 5 mins prior to substrate addition measured after 20 mins by fluorimetric analysis | 2012 | Journal of medicinal chemistry, Jun-28, Volume: 55, Issue:12
| Discovery, structure-activity relationship, and biological evaluation of noninhibitory small molecule chaperones of glucocerebrosidase. |
| AID731592 | Induction of beta glucosidase N370S mutant activity in fibroblasts derived from Gaucher disease patient at 13 uM after 2 days relative to control | 2013 | Journal of medicinal chemistry, Apr-11, Volume: 56, Issue:7
| Pharmacological chaperones as therapeutics for lysosomal storage diseases. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1797733 | GC Enzyme Assay from Article 10.1073/pnas.0705637104: \\Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease.\\ | 2007 | Proceedings of the National Academy of Sciences of the United States of America, Aug-07, Volume: 104, Issue:32
| Three classes of glucocerebrosidase inhibitors identified by quantitative high-throughput screening are chaperone leads for Gaucher disease. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |